What is the Origin of Selank Protocol?

Selank was originally developed in Russia by the Institute of Molecular Genetics as a therapeutic agent for anxiety and asthenia, leveraging the body's natural regulatory peptide systems. The 'Protocol' refers to the specific, clinically determined dosing and administration schedule used to maximize its therapeutic window. Its mechanism of action offers a targeted, physiological approach to neuro-regulation.

What is the Mechanism of Selank Protocol?

Selank's primary mechanism involves modulating the activity of GABAergic and glutamatergic neurotransmitter systems, stabilizing the balance between inhibitory and excitatory signaling in the brain. Crucially, it has been shown to influence the metabolism of enkephalins, preventing their degradation and leading to increased endogenous opioid activity, which contributes to its anxiolytic effect. Furthermore, it is linked to the upregulation of Brain-Derived Neurotrophic Factor (BDNF), promoting synaptogenesis activation and neuronal survival, supporting overall aging brain health.

Selank Protocol

Meaning

The Selank Protocol is a clinical regimen involving the administration of Selank, a synthetic, short-chain peptide analog of the endogenous immunomodulatory neuropeptide tuftsin, primarily utilized for its anxiolytic and nootropic properties. This heptapeptide is clinically recognized for its ability to stabilize mood, enhance cognitive function, and increase mental stamina without the sedative effects associated with traditional anxiolytics. It is often integrated into systemic cognitive improvement strategies.