Selank Peptide Application refers to the clinical or investigational use of Selank, a synthetic, non-narcotic heptapeptide that is an analog of the endogenous human immunomodulatory peptide tuftsin, primarily administered for its pronounced anxiolytic and mild cognitive-enhancing properties. This agent is utilized to address generalized anxiety, improve mental acuity under stress, and stabilize mood without the side effects associated with conventional psychotropic medications.
Origin
Selank was developed by the Institute of Molecular Genetics of the Russian Academy of Sciences as part of a research program focused on leveraging the body’s own regulatory peptides for therapeutic benefit. Its design as a stable, functional analog of tuftsin allowed for targeted application in neurochemical modulation.
Mechanism
The peptide’s primary mechanism involves a multi-faceted action on the central nervous system, most notably by stabilizing the GABAergic system and influencing the balance of monoamine neurotransmitters. Crucially, Selank has been shown to inhibit the enzymatic degradation of enkephalins, endogenous opioid peptides that possess anxiolytic effects. Furthermore, it significantly upregulates the expression of Brain-Derived Neurotrophic Factor (BDNF) in the hippocampus and cortex, supporting long-term neuroplasticity and stress resilience.
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