Selank Nootropic refers to the clinical application of Selank, a synthetic anxiolytic peptide derived from the endogenous human peptide tuftsin, primarily used to enhance cognitive function and reduce anxiety. Classified as a nootropic, it exerts its effects on the central nervous system by modulating neurotransmitter activity and increasing the stability of mental processes. Its use is targeted at improving focus, reducing psychological stress, and supporting overall neuro-vitality.
Origin
Selank was developed in Russia by the Institute of Molecular Genetics of the Russian Academy of Sciences, stemming from research into endogenous regulatory peptides with therapeutic potential. Its origin is rooted in psychopharmacology, where the goal was to create a compound with the beneficial effects of traditional anxiolytics but without the sedative or addictive properties. Its subsequent classification as a nootropic reflects its cognitive-enhancing properties alongside its anxiety-reducing effects.
Mechanism
The peptide functions primarily by modulating the expression and activity of brain-derived neurotrophic factor (BDNF), a key molecule in neuroplasticity and neuronal survival. Selank also influences the metabolism of enkephalins, endogenous opioids that play a role in pain and emotional regulation, leading to an anxiolytic effect. Furthermore, it interacts with the GABAA receptor complex, stabilizing its function and contributing to a balanced, non-sedating reduction in anxiety and improved attentional control.
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