What is the Origin of Selank Mood Stabilization?

Selank is a synthetic analog of the endogenous human peptide tuftsin, developed by the Institute of Molecular Genetics of the Russian Academy of Sciences. Its therapeutic focus on 'Mood Stabilization' emerged from clinical trials demonstrating its potent anxiolytic properties and its unique mechanism of action compared to conventional psychotropic drugs. The development is rooted in the desire for highly specific, non-addictive neuro-modulatory agents.

What is the Mechanism of Selank Mood Stabilization?

Selank's primary mechanism involves the modulation of the GABAergic system and the enhancement of the synthesis and degradation of enkephalins, endogenous opioid peptides with anti-anxiety effects. By inhibiting the enzymatic breakdown of enkephalins, Selank prolongs their action, promoting a sense of calm and well-being. Additionally, the peptide has been shown to influence the expression of Brain-Derived Neurotrophic Factor (BDNF), contributing to its long-term neuroprotective and mood-stabilizing effects.

Selank Mood Stabilization ∞ Area

Selank Mood Stabilization

Meaning

The specific anxiolytic and neuro-regulatory effect of the synthetic peptide Selank, which is clinically utilized to promote emotional equilibrium and reduce generalized anxiety without causing sedation or cognitive impairment. This heptapeptide acts to stabilize the emotional state by modulating the central nervous system’s response to stress and enhancing the body’s intrinsic anti-anxiety mechanisms. It is employed as a targeted intervention for managing chronic stress and emotional volatility.