What is the Origin of Selank for Anxiety?

Selank was developed in Russia by the Institute of Molecular Genetics of the Russian Academy of Sciences as a novel approach to treating generalized anxiety disorder and asthenic-neurotic conditions. Its origin lies in the field of psychoneuroimmunology, based on the discovery that endogenous peptides can exert significant regulatory effects on the central nervous system. It represents a targeted, peptide-based intervention for neuroendocrine balance.

What is the Mechanism of Selank for Anxiety?

The primary anxiolytic mechanism of Selank is believed to involve the modulation of the GABAergic system and the regulation of the balance between pro- and anti-inflammatory cytokines in the central nervous system. Specifically, it has been shown to inhibit the enzymatic degradation of enkephalins, thereby enhancing endogenous opioid activity, which contributes to its mood-stabilizing effects. Furthermore, it influences the expression of Brain-Derived Neurotrophic Factor (BDNF) and directly impacts the serotonin system, contributing to its sustained anti-anxiety and neuroprotective properties.

Selank for Anxiety

Meaning

Selank for Anxiety refers to the clinical application of the synthetic peptide Selank, a heptapeptide analog of the naturally occurring human immunopeptide tuftsin, specifically for the purpose of modulating anxiety and stress-related disorders. Selank is categorized as an anxiolytic and nootropic agent, intended to stabilize emotional states, improve cognitive function under duress, and enhance mental clarity without causing the sedative side effects typical of conventional anxiolytics.