What is the Origin of Sebum Composition?

The term combines "sebum," derived from the Latin word for "fat" or "tallow," with "composition," referring to the elements or ingredients of a mixture. Research into this substance is foundational to dermatology and cosmetic science. The exact ratio of its components is a dynamic physiological variable.

What is the Mechanism of Sebum Composition?

The composition and production rate of sebum are highly regulated by the endocrine system, primarily through the action of androgens like testosterone and dihydrotestosterone (DHT). These hormones bind to receptors on sebocytes, dramatically increasing both the quantity and the lipid profile of the secreted sebum. Conversely, estrogen tends to suppress sebum production. Imbalances, such as those seen in acne or hormone-related skin dryness, are directly linked to changes in this lipid profile.

Sebum Composition ∞ Area

Sebum Composition

Meaning

Sebum composition refers to the precise mixture of lipids, including triglycerides, wax esters, squalene, and cholesterol, that are secreted by the sebaceous glands onto the skin surface. This unique oily substance is crucial for maintaining the skin’s moisture barrier, contributing to its innate antimicrobial properties, and lubricating the hair follicle. Alterations in its composition can significantly impact skin health and disease pathology.