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sCTX

Meaning

sCTX, or serum C-telopeptide of type I collagen, is a specific biochemical marker used in clinical practice to quantify the rate of bone resorption, which is the breakdown of old bone tissue by osteoclasts. As type I collagen is the primary protein component of the bone matrix, the release of its C-terminal telopeptide fragments into the circulation directly correlates with the overall rate of bone turnover. Measuring sCTX is a crucial, objective diagnostic tool for assessing skeletal health and monitoring the effectiveness of osteoporosis treatments.