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SCFA Production Pathways

Meaning

SCFA Production Pathways describe the complex anaerobic metabolic routes by which specific commensal gut bacteria ferment undigested dietary fibers and resistant starches into short-chain fatty acids (SCFAs), primarily acetate, propionate, and butyrate. These pathways are fundamental to the host-microbiome symbiotic relationship, converting otherwise indigestible compounds into vital energy sources and signaling molecules for the host. The efficiency and balance of these pathways are directly correlated with gut health, metabolic function, and systemic inflammation levels. Optimizing these pathways is a central goal in nutritional and microbial therapeutics.