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Scalp Microenvironment

Meaning

The complex, localized biological system encompassing the scalp skin, hair follicles, sebaceous glands, resident microbiome, and the surrounding dermal and vascular structures. This microenvironment is a dynamic interface where hormonal signals, inflammatory mediators, oxidative stress, and mechanical forces interact to regulate the hair growth cycle. Its health is a critical determinant of hair density and quality, and dysregulation is often implicated in common forms of alopecia.