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Sarcopenia Cognitive Decline

Meaning

Sarcopenia Cognitive Decline describes the clinically observed, often bidirectional relationship between the progressive, age-related loss of skeletal muscle mass and strength (sarcopenia) and the simultaneous deterioration of cognitive functions, such as memory and executive control. This link highlights the profound muscle-brain axis, suggesting that skeletal muscle acts as an endocrine organ releasing myokines that influence brain health. Addressing muscle loss is therefore recognized as a critical intervention for mitigating age-related cognitive impairment and supporting overall neurological resilience. This represents a systemic view of aging pathology.