A clinical methodology used to categorize an individual’s propensity for developing specific chronic diseases based on their comprehensive endocrine profile and related biomarker analysis. This process moves beyond standard risk factors by using hormonal imbalances, such as insulin resistance, cortisol dysregulation, or low sex steroid levels, as quantifiable predictors of future cardiovascular, metabolic, or cognitive risk. It is a proactive tool for preventative health.
Origin
This approach is an evolution of preventative medicine and clinical endocrinology, where risk stratification is a standard epidemiological practice. The addition of by Hormones highlights the recognition of the endocrine system as a central integrator of health and disease risk. It provides a more granular, physiological lens for personalized risk assessment.
Mechanism
The mechanism relies on the strong causal link between chronic hormonal dysregulation and pathological processes. For example, elevated morning cortisol and low free testosterone are independently associated with increased visceral fat and cardiovascular risk. By measuring these and other specific hormonal ratios, clinicians can identify individuals in a high-risk category and implement targeted, pre-emptive interventions to modulate the endocrine system, thereby mitigating the projected disease trajectory.
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