Risk Assessment Hormones is a clinical designation for a specific group of hormones whose circulating concentrations or ratios serve as predictive biomarkers for future health risks, including cardiovascular disease, metabolic syndrome, or certain cancers. These hormones, such as elevated insulin, aberrant cortisol, or unfavorable sex hormone ratios, are not merely indicators of current status but potent predictors of long-term morbidity. Monitoring these hormones is a proactive step in preventative health strategy.
Origin
This term is a conceptual tool used in preventative medicine and clinical risk stratification, blending traditional endocrinology with epidemiological data. Its origin is driven by the desire to move beyond standard lipid panels and blood pressure to incorporate more nuanced, mechanism-based biological risk factors.
Mechanism
These hormones are involved in critical homeostatic loops that, when chronically dysregulated, initiate pathological processes. For instance, chronic hyperinsulinemia is a direct driver of endothelial dysfunction and systemic inflammation. By quantifying these hormones, clinicians gain insight into the underlying endocrine-metabolic environment that predisposes an individual to specific age-related diseases, allowing for targeted intervention to normalize the hormonal risk profile.
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