The totality of endocrinological, metabolic, and structural adaptations that occur in response to mechanical loading exercises designed to oppose external force, leading to muscle hypertrophy and increased strength capacity. This is a primary driver of musculoskeletal health and insulin sensitivity.
Origin
This term specifically addresses the body’s reaction to the application of resistance, a foundational concept in exercise physiology and strength science where mechanical stress drives adaptation.
Mechanism
The response involves an acute surge in anabolic hormones like testosterone and growth hormone, followed by sustained activation of muscle protein synthesis pathways mediated by mechanical tension signaling, leading to sarcomere addition and overall muscle fiber growth.
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