What is the Origin of Resistance Training Efficacy?

The term originates from exercise physiology, where "efficacy" denotes the ability of an intervention to produce a desired biological effect under ideal conditions. Its importance in hormonal health stems from the muscle's role as a major site for glucose uptake and anabolic hormone action.

What is the Mechanism of Resistance Training Efficacy?

The primary mechanism involves mechanical tension that initiates muscle damage signals, leading to the activation of the mTOR pathway, which drives protein synthesis and subsequent myofibrillar growth. This mechanical stress also enhances the translocation of GLUT4 transporters to the muscle cell membrane, improving insulin-mediated glucose uptake independent of the systemic insulin concentration. Furthermore, resistance exercise stimulates the pulsatile release of growth hormone and IGF-1, supporting systemic anabolism.

Resistance Training Efficacy

Meaning

Resistance Training Efficacy refers to the measurable physiological benefit derived from structured loading exercises, particularly in terms of promoting muscle hypertrophy, enhancing bone mineral density, and improving systemic insulin sensitivity. High efficacy is characterized by significant increases in lean body mass relative to training volume and recovery investment. This is a cornerstone intervention for mitigating age-related endocrine decline.