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Reproductive Hormone Fluctuation

Meaning

This describes the normal, cyclical, and often pronounced variations in the concentration of sex steroids, such as estrogen, progesterone, and testosterone, and their pituitary regulators, LH and FSH, particularly evident during the menstrual cycle and the perimenopausal transition. While fluctuation is a natural state, excessive or unpredictable variability can lead to symptoms like mood disturbance, irregular cycles, or loss of bone density. Clinical management often focuses on mitigating extreme fluctuations to restore stability and enhance quality of life.