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Reproductive Axis Regulation

Meaning

Reproductive Axis Regulation refers to the complex, hierarchical control system governing the function of the gonads, encompassing the interplay between the hypothalamus, pituitary gland, and the ovaries or testes. This neuroendocrine axis, known as the HPG axis, maintains the production of sex hormones and gametes through a precisely coordinated sequence of releasing and stimulating hormones. Optimal regulation ensures fertility, supports secondary sexual characteristics, and influences overall metabolic and bone health throughout the lifespan. Disruptions in this axis are the basis for many common hormonal and reproductive disorders.