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REM Sleep Testosterone Synthesis

Meaning

REM Sleep Testosterone Synthesis refers to the specific, significant pulsatile release of testosterone that occurs predominantly during the rapid eye movement (REM) phase of sleep in males, which is a critical component of the overall nocturnal testosterone production cycle. This nocturnal peak is essential for maintaining the daily average concentration of circulating testosterone, a primary anabolic hormone that supports muscle mass, bone density, and libido. Disruptions to REM sleep architecture, such as fragmentation or premature termination, can severely attenuate this vital synthetic process, leading to functional hypogonadism.