The clinical measurement of the time interval between the onset of sleep and the beginning of the first period of Rapid Eye Movement, REM, sleep, analyzed specifically for its relationship with neuroendocrine function and psychological state. A shortened REM latency is often a diagnostic marker correlated with various forms of depression and certain hormonal dysregulations, particularly those involving cortisol and melatonin rhythm disruption. It serves as a physiological marker for sleep quality.
Origin
This term originates in sleep medicine and polysomnography, where REM latency is a standard metric for assessing sleep architecture. Correlation is a statistical term, emphasizing the non-causal but predictive relationship between this sleep metric and systemic physiological or psychological conditions. Its relevance in hormonal health is based on the reciprocal relationship between sleep stages and the pulsatile release of hormones.
Mechanism
The correlation mechanism is believed to involve the interplay of neurotransmitters and the HPA axis. Stress-induced elevations in evening cortisol can suppress the onset of deep sleep stages and accelerate the transition to REM sleep, thereby shortening the latency. Furthermore, the timing of REM sleep is linked to thermoregulation and the circadian release of hormones like prolactin and growth hormone, suggesting a direct neuroendocrine influence on its initiation.
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