The concerted effort to support and enhance the body’s inherent ability to repair damaged tissues, replace senescent cells, and restore functional integrity across organ systems, largely driven by optimal growth factor and endocrine signaling. This is about fostering self-renewal potential.
Origin
This concept is rooted in regenerative medicine, focusing on maximizing the innate biological mechanisms—like stem cell mobilization and tissue remodeling—that contribute to long-term vitality and resilience. Maximization implies pushing these natural limits.
Mechanism
This is achieved by optimizing the hormonal environment, ensuring robust levels of anabolic signals like testosterone and growth hormone, while simultaneously mitigating inhibitory signals such as excessive cortisol or systemic inflammation. Adequate substrate availability for cellular turnover is also paramount to this process.
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