The Red Blood Cell Count, or erythrocyte count, is a common hematological test that quantifies the total number of red blood cells present in a specific volume of blood, typically expressed as cells per microliter. These cells are crucial for systemic oxygen transport, as they contain hemoglobin, the protein responsible for binding oxygen in the lungs and releasing it to peripheral tissues. This count is a key diagnostic component of the Complete Blood Count (CBC), reflecting both bone marrow activity and oxygen-carrying capacity.
Origin
This is a fundamental clinical term in hematology, a branch of medicine studying blood and blood-forming organs. The practice of counting blood cells dates back to the invention of the microscope and the development of standardized laboratory techniques.
Mechanism
The count is regulated by a negative feedback loop involving the hormone Erythropoietin (EPO), primarily secreted by the kidneys in response to tissue hypoxia. Low oxygen levels stimulate EPO release, which then acts on progenitor cells in the bone marrow to accelerate the production and maturation of new red blood cells. Hormones such as testosterone can also stimulate erythropoiesis, contributing to higher counts and enhanced oxygen delivery, a factor relevant to strength and endurance.
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