Recovery and Repair encompasses the coordinated physiological processes, heavily influenced by anabolic hormones like growth hormone and testosterone, necessary to restore tissues to their pre-stress or pre-injury functional state. This phase involves the synthesis of new proteins, cellular regeneration, and the resolution of localized inflammation following catabolic events such as intense physical exertion or acute illness. It is the constructive counterpart to metabolic challenge.
Origin
These words derive from the Latin roots meaning ‘to get back’ (recover) and ‘to mend’ (repair). In physiology, this pairing denotes the systemic shift from energy mobilization to tissue building and restoration. The endocrine system plays the pivotal role in orchestrating this anabolic shift following periods of energy expenditure or damage.
Mechanism
The mechanism centers on the pulsatile release of anabolic mediators that activate cellular machinery for protein synthesis, primarily through the mTOR pathway. Growth hormone stimulates the liver to produce Insulin-like Growth Factor 1 (IGF-1), which drives cellular proliferation and repair processes in peripheral tissues. Adequate sleep and proper nutrient timing further support this hormonal cascade, ensuring efficient DNA repair and structural restoration at the molecular level.
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