Skip to main content

Receptor Translocation Efficiency

Meaning

The quantifiable measure of how effectively and rapidly a hormone or signaling molecule receptor, upon binding its ligand, moves from its initial location (typically the cell membrane or cytoplasm) to its site of action, usually the cell nucleus, to initiate a biological response. This efficiency is a critical determinant of cellular responsiveness and hormonal efficacy, as poor translocation can lead to functional resistance despite adequate hormone levels. Age and chronic inflammation often impair this crucial cellular process.