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Receptor Site Affinity Enhancement

Meaning

Receptor Site Affinity Enhancement describes a molecular event where the binding strength between a circulating ligand, such as a hormone, and its specific receptor protein on a target cell surface or within the nucleus is increased. This molecular tightening allows the hormone to exert its biological effect more potently or at lower concentrations than previously possible. Maximizing affinity is a fundamental goal in pharmacology and physiological optimization. This ensures efficient signal transmission across the cell membrane barrier.