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Receptor Sensitivity Monitoring

Meaning

Receptor Sensitivity Monitoring is a precise, individualized clinical and diagnostic strategy focused on assessing the functional responsiveness of target cells to specific hormonal or neurotransmitter signals, rather than solely measuring the concentration of the circulating ligand. This process evaluates the cellular capacity of receptors to effectively bind their ligands and successfully initiate the appropriate intracellular signaling cascade. Monitoring this sensitivity is critical because a normal circulating hormone level can be functionally insufficient if the corresponding receptor population is desensitized or down-regulated.