Skip to main content

Receptor Sensitivity Assessment

Meaning

Receptor Sensitivity Assessment is the clinical and molecular evaluation of a cell’s or tissue’s responsiveness to specific hormonal or signaling molecules, determining the efficiency of the ligand-receptor binding and subsequent intracellular cascade. This assessment is critical because high circulating hormone levels are meaningless if the target receptors are downregulated or desensitized. Clinically, optimizing this sensitivity is often more impactful than merely increasing hormone concentrations.