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Receptor Modulation

Meaning

Receptor Modulation is the fundamental biological or pharmacological process of altering the activity, number, or sensitivity of cellular receptors to influence the magnitude of a cellular response to a hormone or neurotransmitter. This essential mechanism dictates how effectively endocrine signals are translated into cellular action. Modulation can involve up-regulation, down-regulation, or changing the conformational state of the receptor itself, thereby adjusting the cellular response threshold.