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Receptor Density Profiling

Meaning

Receptor Density Profiling is the clinical assessment of the number and distribution of specific hormone receptors on the surface and within target cells, such as those for androgens, estrogens, or thyroid hormones. This profiling provides crucial insight into the actual cellular responsiveness to circulating hormones, which is often a more accurate measure of hormonal effect than the mere concentration of the hormone itself. Low receptor density, a form of endocrine resistance, can impede even high levels of circulating hormones from exerting their biological action.