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Rebound Weight Gain

Meaning

Rebound weight gain is the rapid and often excessive regain of lost body mass following the cessation of a period of significant caloric restriction or aggressive weight loss intervention. This common physiological phenomenon is driven by complex compensatory hormonal and metabolic adaptations that vigorously defend the body’s established weight setpoint. Clinically, it represents a failure of long-term weight maintenance and a challenge to metabolic stability. Understanding this powerful homeostatic defense is crucial for designing sustainable weight management strategies.