A targeted clinical or lifestyle intervention focused on deliberately resetting or adjusting an individual’s desynchronized circadian rhythms, especially the sleep-wake cycle and the corresponding hormonal secretion patterns. This process aims to restore the correct timing and appropriate amplitude of the cortisol diurnal variation and the nocturnal melatonin release. Successful re-entrainment is essential for improving metabolic health, cognitive function, and deep sleep window optimization.
Origin
The term is derived from chronobiology, where entrainment refers to the synchronization of an endogenous biological rhythm to an external environmental cue, such as the light-dark cycle. Cycling refers to the repeated process of intervention and monitoring required for stable adjustment. It is a clinical response to circadian disruption.
Mechanism
The primary mechanism involves controlled manipulation of light exposure, which signals the suprachiasmatic nucleus, the body’s master biological clock. Timed interventions, such such as specific light exposure protocols or low-dose melatonin administration, can assist in stabilizing the rhythm. Re-entrainment is a powerful tool for mitigating the systemic dysregulation caused by shift work, jet lag, or chronic poor sleep habits.
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