What is the Origin of RAS?

The components of the RAS were identified through systematic physiological research focused on understanding how the kidneys modulate systemic circulatory dynamics. Its etymology derives from the enzymes and substrates involved in its cascade, particularly renin.

What is the Mechanism of RAS?

The mechanism initiates when renal juxtaglomerular cells release renin in response to low perfusion pressure, leading to the conversion of angiotensinogen to Angiotensin I, subsequently processed by ACE into the potent vasoconstrictor Angiotensin II. Furthermore, Angiotensin II stimulates the adrenal cortex to secrete aldosterone, profoundly influencing sodium and water retention, thereby modulating overall fluid balance.

RAS

Meaning

RAS most precisely refers to the Renin-Angiotensin System, a pivotal hormonal cascade within human physiology responsible for the long-term regulation of systemic blood pressure, fluid homeostasis, and electrolyte balance. This system is a key target for managing cardiovascular and renal function. It represents a crucial endocrine regulatory loop.

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RAS

Meaning

Origin

Mechanism

How Do Legal Frameworks Differentiate Wellness Program Incentives?

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