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Pulmonary Arterial Hypertension

Meaning

Pulmonary Arterial Hypertension (PAH) is a severe, progressive clinical condition characterized by an abnormally high blood pressure specifically within the arteries of the lungs, those carrying blood from the right side of the heart. This chronic and dangerous elevation in pressure leads to severe right-sided heart strain, eventual heart failure, and a significant limitation of exercise capacity and longevity. While primarily a life-threatening cardiovascular disorder, it can have complex hormonal and inflammatory underpinnings, particularly in certain susceptible patient populations.