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PT-141 for Libido

Meaning

PT-141, also known by its generic name Bremelanotide, is a synthetic peptide used clinically to treat hypoactive sexual desire disorder (HSDD) in premenopausal women and, off-label, for sexual dysfunction in men. It functions as a melanocortin receptor agonist, specifically targeting the MC3R and MC4R receptors in the central nervous system, bypassing the vascular effects associated with traditional erectile dysfunction medications. The administration of PT-141 is designed to enhance sexual desire and arousal by modulating neural pathways in the brain. It represents a neuro-hormonal approach to managing complex sexual health issues. This is a novel therapeutic mechanism in sexual medicine.