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Psychosocial Stress Impact

Meaning

The measurable effect of psychological and social environmental factors, such as relationship conflict, work pressure, or financial insecurity, on the physiological stress response systems of the body. This impact is primarily mediated through the chronic activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis and the sympathetic nervous system, leading to sustained hormonal and autonomic dysregulation. It quantifies how lived experience translates into biological change.