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Psychosocial Stress Biomarkers

Meaning

Psychosocial Stress Biomarkers are measurable biochemical and physiological indicators that reflect the body’s systemic response to psychological and social challenges, such as chronic work pressure, relationship conflict, or perceived threat. These markers extend beyond simple cortisol measurement to include inflammatory cytokines, specific neurotransmitter metabolites, heart rate variability (HRV) patterns, and epigenetic changes. The clinical utility lies in objectively quantifying the cumulative allostatic load imposed by an individual’s life circumstances, providing a concrete link between mental experience and physical health outcomes. Analyzing these biomarkers allows for personalized, targeted stress mitigation strategies.