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Psychoneuroendocrine Feedback

Meaning

Psychoneuroendocrine feedback is the complex, bidirectional communication system that links psychological states, the central nervous system, and the endocrine system, creating an integrated regulatory loop. This mechanism illustrates how stress, emotion, and cognitive processes directly influence hormone secretion, and conversely, how hormonal balance profoundly affects mood, behavior, and mental health. Clinically, this feedback loop is crucial for understanding conditions like chronic fatigue, anxiety, and stress-related hormonal dysregulation.