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Psychological Stress Physiology

Meaning

Psychological Stress Physiology is the study of the integrated neuroendocrine and autonomic responses elicited by cognitive and emotional stressors, examining how perceived threats translate into measurable physiological changes. This field focuses on the activation of the hypothalamic-pituitary-adrenal (HPA) axis and the sympathetic nervous system, leading to the release of cortisol, catecholamines, and other stress mediators. Understanding this physiology is crucial because chronic psychological stress drives significant hormonal imbalance and systemic inflammation. The body does not distinguish between physical and emotional threats.