The neurobiological capacity of an individual to maintain stable cognitive function, emotional equilibrium, and effective stress coping mechanisms despite exposure to psychological stressors or physiological challenges. This resilience is intrinsically linked to neuroendocrine balance, particularly the regulation of neurotransmitters and the HPA axis. It is a critical metric for assessing mental well-being and adaptive capacity.
Origin
The term combines ‘psychological state,’ referring to the mental and emotional condition, with ‘resilience,’ a concept borrowed from materials science and psychology, denoting the ability to recover quickly from difficulties. In the context of hormonal health, it highlights the profound influence of the endocrine system on mood and cognition.
Mechanism
Resilience is fundamentally mediated by the efficient regulation of the stress response system. A robust mechanism involves the rapid and appropriate release and clearance of cortisol and catecholamines in response to stress, followed by a swift return to baseline. Furthermore, optimal levels of neurosteroids and key neurotransmitters, like serotonin and dopamine, ensure stable mood and cognitive processing, allowing the individual to effectively adapt to adversity without sustained emotional or cognitive deficit.
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