This refers to the specific cohort of endocrine molecules that are essential for sustaining mental and emotional energy, maintaining focus under prolonged stress, and supporting the psychological capacity for long-term goal pursuit. These hormones are the physiological foundation of mental endurance and resilience against burnout. Optimizing this hormonal profile is a clinical strategy for enhancing an individual’s total psychological work capacity.
Origin
The concept is a practical, clinical application of stress endocrinology and neuroendocrinology, acknowledging that psychological persistence is a biologically supported trait. It draws from the observation that individuals with robust hormonal profiles, particularly in their stress and sex hormone axes, demonstrate greater emotional and cognitive resilience. The term is designed to translate complex science into actionable clinical goals.
Mechanism
The primary hormones include a healthy diurnal rhythm of cortisol, which provides sustained energy and anti-inflammatory support, and robust levels of DHEA-S, which acts as a neuroprotective and mood-enhancing counter-regulatory hormone to cortisol. Additionally, optimized thyroid hormone levels ensure the necessary metabolic rate for sustained brain function. The collective action of these hormones buffers the nervous system against chronic fatigue and preserves the capacity for executive function.
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