What is the Origin of Psychological Sequelae?

The term is a combination of the domain "Psychological," referring to the mind and behavior, and the Latin-derived medical term "Sequelae," which means a condition that is the consequence of a previous disease or injury. Its use in medicine acknowledges that a physical event or diagnosis often has lasting, non-physical impacts on an individual's mental and emotional state. This emphasizes the need for holistic patient care.

What is the Mechanism of Psychological Sequelae?

The development of psychological sequelae is mechanistically linked to the chronic activation of the hypothalamic-pituitary-adrenal (HPA) axis, leading to persistent dysregulation of stress hormones like cortisol. Furthermore, the experience of trauma or chronic illness can induce neurobiological changes, including alterations in brain structure and function, particularly in regions responsible for emotional regulation and memory. The prolonged emotional burden contributes to a cycle of chronic stress and impaired mental well-being.

Psychological Sequelae ∞ Area

Psychological Sequelae

Meaning

The enduring psychological and emotional consequences, or after-effects, that follow a significant physical or emotional trauma, a major medical diagnosis, or a prolonged period of physiological stress. These sequelae can manifest as chronic conditions, including persistent anxiety, depression, post-traumatic stress disorder, or significant alterations in body image and self-esteem. In hormonal health, this term is frequently used to describe the long-term mental health burden associated with infertility, chronic endocrine disorders, or cancer treatment.