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Psychobiome Engineering

Meaning

The deliberate and systematic manipulation of the gut microbiota and its metabolic activity to positively influence the host’s mood, cognition, and behavior via the gut-brain axis. Engineering involves utilizing prebiotics, probiotics, or dietary changes to modulate the production of neuroactive compounds and reduce systemic neuroinflammation. This is a novel, high-impact area in neuroendocrinology and mental health.