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Proteomic Aging Clock

Meaning

The Proteomic Aging Clock is a sophisticated biological measure that estimates an individual’s biological age, often termed physio-age, by quantifying the abundance and modification status of hundreds or thousands of specific proteins circulating in the plasma or found in various tissues. Unlike genetic clocks, this method measures the functional output of the genome, providing a snapshot of the current physiological state, cellular damage, and systemic inflammation. It serves as a highly predictive biomarker for all-cause mortality and chronic disease risk.