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Proteinuria

Meaning

Proteinuria is a clinical finding characterized by the presence of abnormally high concentrations of protein, primarily albumin, in the urine. This condition serves as a significant indicator of compromised glomerular filtration or impaired tubular reabsorption within the kidneys, suggesting underlying renal damage or systemic disease. Clinically, proteinuria is a key diagnostic and prognostic marker for chronic kidney disease (CKD), hypertension, and diabetes, often reflecting a critical imbalance in the renal filtration barrier. Persistent, elevated levels warrant immediate investigation to prevent further decline in kidney function.