Skip to main content

Protective Gene Activation

Meaning

Protective Gene Activation refers to the targeted biological process of up-regulating the expression of specific genes whose protein products confer enhanced cellular resilience, DNA repair capacity, and resistance to metabolic stress and age-related pathology. These genes often include those involved in antioxidant defense, heat shock response, and sirtuin activity, which collectively function to maintain genomic stability and mitochondrial integrity. In the context of hormonal health, this activation is often triggered by hormetic stressors, such as specific nutritional compounds or controlled temperature exposure, acting as a potent non-pharmacological strategy to promote longevity and cellular rejuvenation.