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Prostate Cellular Turnover

Meaning

Prostate cellular turnover refers to the continuous, balanced process of cell division (proliferation) and programmed cell death (apoptosis) that maintains the size and functional integrity of the prostate gland. This delicate equilibrium is essential for normal tissue homeostasis, ensuring that old or damaged cells are replaced at a rate that prevents both atrophy and hyperplasia. The turnover rate is profoundly influenced by the endocrine environment, particularly by androgens like testosterone and dihydrotestosterone (DHT). Disruption of this balance, often seen with age and hormonal changes, is a precursor to conditions like benign prostatic hyperplasia (BPH) and prostate cancer.