What is the Origin of Prolactin Level Assessment?

This practice is foundational to neuroendocrinology, as Prolactin is primarily secreted by pituitary lactotrophs and is regulated by a tonic inhibitory control, chiefly from hypothalamic dopamine. The assessment is a routine part of investigating reproductive dysfunction and pituitary disorders.

What is the Mechanism of Prolactin Level Assessment?

The assessment quantifies the circulating Prolactin, a hormone whose primary function is lactation, but whose elevation, known as hyperprolactinemia, exerts a powerful inhibitory effect on the hypothalamic-pituitary-gonadal (HPG) axis. High Prolactin levels suppress GnRH pulsatility, leading to decreased sex hormone production and symptoms like hypogonadism or amenorrhea. The measurement helps identify causative factors, including pituitary adenomas, certain medications, or primary hypothyroidism.

Prolactin Level Assessment ∞ Area

Prolactin Level Assessment

Meaning

Prolactin Level Assessment is a standard diagnostic procedure involving the precise measurement of the concentration of the peptide hormone Prolactin in the circulating blood. This assessment is clinically necessary for evaluating the functional status of the anterior pituitary gland and its regulatory relationship with the hypothalamus. Abnormal levels can indicate significant endocrine or neuroendocrine pathology.