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Prolactin Inflammatory Response

Meaning

The Prolactin Inflammatory Response describes the multifaceted immunomodulatory role of the pituitary hormone prolactin, which, in addition to its classic reproductive functions, can act as a pro-inflammatory cytokine under certain conditions. While prolactin supports essential immune function under normal, homeostatic circumstances, chronically elevated or dysregulated levels can significantly exacerbate systemic inflammation and contribute to the pathology of autoimmune diseases. Understanding this dual response is crucial in the clinical management of hyperprolactinemia and associated inflammatory states.