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Progestin Receptor Health

Meaning

Progestin Receptor Health refers to the optimal functional status and high responsiveness of the intracellular progesterone receptors (PR-A and PR-B) located in key target tissues such as the uterus, breast, and central nervous system. Maintaining a healthy receptor density and high sensitivity is paramount for the body to fully utilize circulating progesterone, which is essential for endometrial stability, regular reproductive cycles, and critical neuroprotection. Dysregulation in receptor health can clinically lead to a state of progesterone resistance, even in the presence of adequate hormone levels.