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Progesterone’s Anxiolytic Effects

Meaning

Progesterone’s Anxiolytic Effects describe the natural, calming, and anxiety-reducing properties mediated by the hormone progesterone and, more potently, its neuroactive metabolite, allopregnanolone, within the central nervous system. This action is distinct from its primary reproductive functions and is critical for regulating mood stability, sleep quality, and the body’s physiological response to stress. Clinically, a decline in progesterone levels is often correlated with increased anxiety and sleep disturbances, particularly during the late luteal phase and perimenopause.