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Progesterone Timing Considerations

Meaning

Progesterone timing considerations refer to the critical clinical assessment of the optimal administration schedule for progesterone therapy, which is essential for maximizing its therapeutic benefits and minimizing potential side effects, particularly in women. Because progesterone has a profound impact on the sleep cycle, mood, and endometrial tissue, its timing must align with the body’s natural circadian and infradian rhythms. For instance, nocturnal dosing is often preferred to leverage its sedative and anxiolytic properties.