Skip to main content

Progesterone Status Monitoring

Meaning

Progesterone Status Monitoring is the systematic, often longitudinal, clinical assessment of circulating progesterone levels and its key metabolites to accurately determine a patient’s functional progesterone status across the menstrual cycle or during hormone replacement therapy. This monitoring is essential for evaluating luteal phase adequacy in reproductive health and for ensuring therapeutic efficacy and safety in menopausal hormone therapy, particularly in endometrial protection. Precise status monitoring requires consideration of the hormone’s pulsatile release, the assay method used, and the clinical context, moving beyond a single, isolated blood test. It provides the necessary data to personalize dosing and administration timing for optimal physiological effect.